Sarah Reading, M.D. Assistant Professor Address: 600 N. Wolfe St., Phipps 313, Baltimore, MD 21287 Phone: 410-502-6944 Fax: 410-614-3676 Email: sreading@jhmi.edu

Who Am I?

Sarah Reading, MD is a Faculty member in the Department of Psychiatry and Behavioral Sciences at Johns Hopkins University School of Medicine. Dr. Reading is an active full-time staff member in Psychiatry at the Johns Hopkins Hospital. She is involved in research using Diffusion Tensor Imaging (DTI), a new technology used to image white matter tracts, as well as fMRI and cognitive activation. She is interested in examining the structural and functional correlates to cognitive abnormalities in patients with Schizophrenia, Bipolar disorder and Huntington's Disease.

Active Projects

• An examination of functional (fMRI) and structural (DTI) brain changes in presymptomatic and early Huntington's disease.
  
• An examination of functional (fMRI) and structural (DTI) brain changes in familial Bipolar disorder.
  
• An examination of funtional (FMRI) and structural (DTI) brain changes associated with the interaction of Herpes Simplex Virus, type 1 (HSV-1) and COMT allelic variation in Bipolar disorder.
  
• An examination of the relationship between frontal lobe function (fMRI) and white matter integrity (DTI) in Schizophrenia
  
• An examination of the relationship between DTI data and fMRI data in relationship to each other and to clinical variables in neuropsychiatric populations

Selected Publications

• Reading SA, Yassa MA, Bakker A, Dziorny AC, Gourley LM, Yallapragada V, Rosenblatt A, Margolis RL, Aylward EH, Brandt J, Mori S, van Zijl P, Bassett SS, Ross CA. Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor study. Psychiatry Research: Neuroimaging (in press).
• Reading SA, Little JT. "Psychosis secondary to infections" in The Spectrum of Psychotic Disorders: Neurobiology, Etiology & Pathogenesis, Fujii D, Ahmed I, editors; Cambridge University Press (in press).
• Kim J-S, Reading S, Brashers-Krug T, Calhoun V, Ross CA, Pearlson GD. Functional MRI study of a serial reaction time task in Huntington's disease. Psychiatry Research: Neuroimaging 131:23-30, 2004.
• Reading S, Dziorny A, Peroutka L, Schreiber M, Gourley L,Yallaprada V, Rosenblatt A, Margolis R, Pekar J, Pearlson G, Aylward EH, Brandt J, Bassett S, Ross C. Functional Brain Changes in Pre-Symptomatic Huntington's Disease. Functional brain changes in pre-symptomatic Huntington's disease. Annals of Neurology 55:879-883, 2004.