Laura Marsh, M.D. Associate Professor Address: 600 N. Wolfe St., Phipps 300C, Baltimore, MD 21287 Phone: 410-502-6945 Fax: 410-614-3676 Email: lmarsh@mail.jhmi.edu

Who Am I?

Laura Marsh, M.D. is an Associate Professor in the Department of Psychiatry and Behavioral Sciences and in the Department of Neurology at Johns Hopkins University School of Medicine in Baltimore, Maryland. She directs and is the principal investigator of the Clinical Core Research Program of the NIH-funded Morris K. Udall Parkinson's Disease Research Center of Excellence at Johns Hopkins (P.I., Ted Dawson, M.D., Ph.D.). In addition to her affiliation with the Division of Psychiatric Neuroimaging, Dr. Marsh is an Attending Psychiatrist with the Geriatric Psychiatry and Neuropsychiatry Division at the Johns Hopkins University School of Medicine and a faculty member of the Johns Hopkins Parkinson's Disease and Movement Disorders Center, which has been designated a Center of Excellence by the National Parkinson Foundation. Dr. Marsh is also a member of the scientific advisory boards for the American Parkinson's Disease Foundation and the Leeza Gibbons Memory Foundation.

Dr. Marsh's clinical and academic research interests focus on Neuropsychiatry and she has specific expertise in the neuropsychiatric aspects of Parkinson's disease and of epilepsy. Her current work focuses on the psychiatric aspects of Parkinson's disease, with her primary research and outreach efforts aimed at improving the recognition and treatment of psychiatric and cognitive disturbances in Parkinson's disease. She is also investigating the relationships between motor, psychiatric, and cognitive aspects of PD and their relationship to the longitudinal course of the disease.

Active Projects

• Principal Investigator, "Methods of Optimal Depression Detection in Parkinson's" (MOOD-PD)
  Sponsor: NIH (NIMH/RO1 MH06966)
• Principal Investigator, Clinical Core Research Program, Morris K. Udall Parkinson's Disease
  Research Center (Center PI, Ted Dawson)
  Sponsor: NIH (NINDS PO1 NS-58377)
  Primary Core Projects: Longitudinal Study of Parkinson's Disease, Brain Donation
  Registry; DNA repository; Database registry
  
• Principal Investigator, "Atomoxetine for treatment of executive dysfunction in Parkinson's
  Disease: An open label study"
  Sponsor: Eli Lilly and Company, Committee of Investigator-initiated studies
  
• Principal Investigator, "Double-blind placebo-controlled trial of memantine for treatment of
  cognitive impairment in patients with Parkinson's disease and dementia"
  Sponsor: Forest Pharmaceuticals Investigator-initiated trial Program
• Co-investigator, "Disability in Parkinson's Disease"
  Sponsor: NIH R01-HD39822
  Principal Investigator: Susan Bassett, Ph.D.
• Faculty Director, Outreach Program, Parkinson's Disease Center of Excellence
  Sponsor: National Parkinson Foundation
  

Selected Publications

• Marsh L, McDonald WM, Cummings J, Ravina B, NINDS/NIMH Work Group on Depression and Parkinson's Disease. Provisional Diagnostic Criteria for Depression in Parkinson's Disease: Report of an NINDS/NIMH Work Group. Movement Disorders, In press.
  
• Menza MM, Marsh L (Editors). Psychiatric Issues in Parkinson's Disease: A Practical Guide. Taylor and Francis, London. 2005.
  
• Marsh L. Psychosis in Parkinson's disease. Primary Psychiatry 2005, 12 (7), 58-64.
  
• Marsh L, Margolis R. Neuropsychiatric aspects of movement disorders in Comprehensive Textbook of Psychiatry, 8th edition BI Sadock, VI Sadock (eds). Lippincott, Williams, and Wilkins: New York, 2005, 403-423.
  
• Marsh L, Williams JR, Rocco M, Grill S, Munro C, Dawson TM. Psychiatric co-morbidities in patients with Parkinson's disease and psychosis. Neurology 2004; 63: 293-300.
  
• Leroi I, Brandt J, Reich SG, Grill S, Thompson R, Marsh L. Randomized placebo-controlled trial of donepezil for cognitive impairment in Parkinson's disease. International Journal of Geriatric Psychiatry 2004; 19:1-8.
  
• Reich SG, Marsh L. Ten most commonly asked questions about the psychiatric aspects of Parkinson's disease. The Neurologist 2003; 9: 50-56
  
• Marsh L, Berk A. Neuropsychiatric aspects of Parkinson's disease: recent advances. Current Psychiatry Reports 2003; 5: 68-76.
  
• Marsh L, Rao V. Psychiatric complications in patients with epilepsy: a review. Epilepsy Research, 2002; 49: 11-33
  
• Marsh L, Dawson TM. Treatment of early Parkinson's disease (editorial) British Medical Journal. 2000; 321:1-2.
  
• Marsh L (Guest Editor). Parkinson's Disease and its neuropsychiatric features. International Review of Psychiatry. 2000; 12: 261-262
  
• Marsh L. Anxiety Disorders in Parkinson's Disease. International Review of Psychiatry 2000; 12: 307-308.